When it comes to math, the modern eCRF is no slouch. You’ve seen OpenClinica forms add, substract, multiply, and divide values at lightning speed. But these operations barely scratch the service.
OC4’s form engine supports a wide array of mathematical functions, from arcsins to exponents, all defined by clear, human-readable expressions. What does this mean for your clinical trial? As the data manager, you can help your site users derive complex measures, like the one below, with a consistent, error-free method. Meanwhile, site users never need to launch their calculator app or recall the right formula to apply.
The example below relies on a combination of “if then” logic and calculation to (1) identify the formula relevant to the participant’s race, sex, and serum creatinine, and (2) apply the formula to the input supplied by the user. The form completes both of these tasks in milliseconds. Give it a try!
Did you know? Glomerular filtration rate (GFR) is an estimate of how much blood passes through the glomeruli of the kidneys each minute. It is an indicator of kidney function. For adults between the ages of 20 and 59, a GFR below 90 mL/min/1.73m2 may suggest kidney disease, depending on whether other signs of kidney damage (e.g. protein in urine) are present. (Source: “Glomerular Filtration Rate: A Key to Understanding How Well Your Kidneys Are Working” from the National Kidney Foundation)
You can find an authoritative compendium of measures like this at MD+CALC, all of which can be implemented in OpenClinica forms.